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Advancing the use of noncoding RNA in regulatory toxicology: Report of an ECETOC workshop
The European Centre for the Ecotoxicology and Toxicology of Chemicals (ECETOC) organised a workshop to discuss the state-of-the-art research on noncoding RNAs (ncRNAs) as biomarkers in regulatory toxi...
Adapting SimpleTreat for simulating behaviour of chemical substances during industrial sewage treatment
The multimedia model SimpleTreat, evaluates the distribution and elimination of chemicals by municipal sewage treatment plants (STP). It is applied in the framework of REACH (Registration, Evaluation,...
Future needs and recommendations in the development of species sensitivity distributions: Estimating toxicity thresholds for aquatic ecological communities and assessing impacts of chemical exposures.
A species sensitivity distribution (SSD) is a probability model of the variation of species sensitivities to a stressor, in particular chemical exposure. The SSD approach has been used as a decision s...
Workshop Report no.31: Advances in Consumer Exposure Science: Data, Modelling and Aggregate Exposure Assessment. 26th January 2016, Brussels
This workshop report summarises a workshop held in Brussels on 26th January 2016 by the ECETOC Human Exposure Data Task Force on the state of the art of consumer exposure assessment science as develop...
Workshop Report no.30: The Role of Epigenetics in Reproductive Toxicity
This workshop explored the current state of the science on epigenetics and its role in reproductive toxicity. Experts from a range of scientific disciplines met over two days to share knowledge and br...
Special Report no.19: Building a Prenatal Developmental Toxicity Ontology
This report discusses the need for a systematic representation of knowledge about developmental toxicity (i.e. an ontology) that would enable computer-based prediction of which chemicals are likely to...
Workshop Report no.29 – Defining the role of chemical activity in environmental risk assessment within the context of mode of action: Practical guidance and advice
Chemical activity has recently been promoted as a useful concept for interpreting and classifying ecotoxicological data and for performing environmental risk assessment of chemicals. The most common...
Technical Report no.125 – Chemical Risk Assessment – Ecosystems Services
Ecosystem goods and services are the benefits we (humans) get from nature. They include provisioning services, e.g. from crops that provide food and fibre, regulating services, e.g. the plants growing...
Case studies putting the decision-making framework for the grouping and 4 testing of nanomaterials (DF4nanoGrouping) into practice
ECETOC concept allows assessing the safety of nanomaterials undertaking animal testing only as a very last resort Brussels, December 2015 The safety of nanomaterials can be ensured by testing...
Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals
Brussels, October 2015 In a Nutshell: The relationship between the toxicity of narcotic chemicals and the octanol water partition coefficient (KOW) has been widely explored. An alternative but close...
From Bioavailability Science to Regulation of Organic Chemicals
Ortega-Calvo JJ, Harmsen J, Parsons JR, Semple KT, Aitken MD, Ajao C, Eadsforth C, Galay Burgos M, Naidu R, Oliver R, Peijnenburg WJ,, Römbke J, Streck G, Versonnen B. 2015. From Bioavailability Scie...
Thresholds in chemical respiratory sensitisation
Brussels, May 2015 A variety of chemicals are known to cause allergic sensitisation of the respiratory tract associated with allergic rhinitis and asthma. It is generally accepted that the development...
A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)
The safety of nanomaterials can be ensured by undertaking animal testing only as a very last resort. This is the premise and promise of the Decision-making framework for the grouping and testing of na...
